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he final volume of the FIBRINOGEN MEMOIRS trilogy.
In Fibrinogen Memoirs 3, the author chronicles stories and experiences that are linked to a single life-changing event that occurred shortly after he had graduated from medical school at SUNY-Downstate Medical Center. That event and its consequences are detailed in the book’s first chapter. The subtitle, Ripples On The Water, serves as a metaphor for the experiences and accomplishments that would not have occurred if not for that singular event.
The chapters include a story about one of the inventors of Magnetic Resonance Imaging (MRI) who was a wannabe Nobel laureate, one about The Milwaukee Heart Project that resulted in successful design and development of a total artificial heart device (TAH), and another that concerned the actions of a rogue investigator whose unprecedented antics undermined and disrupted the peer review process.
In another chapter the author relates some events that accompanied the decline of the fibrin cross-linking controversy, a topic that was the main subject of the second volume in this series. There is also a chapter describing the achievements of Jim Maroney, an aviation legend, and one describing the author’s role in performing cardio-pulmonary resuscitation (CPR) on a golf course and the subsequent fallout following the CPR.
He also provides an account of his courtship and marriage to Shirley Ann McDowell that detailed his recovery from grief after her death. That account was followed by a related story about the provenance of a spiritual fantasy concerning his grandson, Sebastian Eckmann. The final chapter, Life with The Temkin Tribe, is about a long and convoluted relationship with Libby Temkin and other members of her ‘tribe’. Together, these stories offer a rich tapestry that provides unique insights into Michael Mosesson’s character, his personal and professional relationships, his values, and some of his scientific accomplishments.
Previous volumes by Michael W. Mosesson:
Book #1:
The Fibrinogen Memoirs: Journeys of a Clot Doctor
This book covers many aspects of Mosesson’s career experiences, stories often narrated in terms of personal interactions. Its chapters reveal previously unrecognized aspects of interactions and controversies that drive and motivate the scientific investigative process. The author writes:
“I began writing these essays and monographs about eight years ago, soon after it became evident that my days as an active laboratory investigator at the Blood Research Institute were ending. In writing these monographs I hoped to convey how and why I became who I was as a physician/scientist investigating Fibrinogen, Thrombosis, and Fibrinolysis. During the course of my scientific career I encountered numerous challenges and issues, many of which were solved or resolved, some others not. In these narrations I combined a personal account of events, people, my family, and circumstances that surrounded and influenced these subjects. I have also written a chapter on my flying career which began shortly after I had moved to NIH in 1961, and ended more than fifty years later.”
Book #2:
Fibrinogen Memoirs The Rise and Fall of the Fibrin Cross-linking Controversy concerns the longstanding controversy over the arrangement of ‘cross-linked’ structures within fibrin clots. The narrative covers the period from its origins to its unexpected decline and demise. The decades-long unresolved dispute over whether the cross-links were arranged in a ‘longitudinal’ or a ‘transverse’ position was replaced by the dogma that they were ‘longitudinal’, a structural arrangement that could not account for fibrin’s known elastic properties. The alternative bond arrangement, transverse, was no longer mentioned, despite an overwhelming body of evidence for its existence. This realization, coupled with the understanding that only a transverse bond arrangement could account for fibrin elasticity, prompted the Author to write the second volume of Fibrinogen Memoirs.
ABOUT THE AUTHOR:
Michael Mosesson grew up in Brooklyn, New York. He earned a medical degree at SUNY Downstate Medical Center, and afterward spent more than fifty years as a hospital/medical school-based physician, teacher, and scientist. His clinical activities included internal medicine and hematology, with special attention to bleeding and thrombotic disorders, and fibrinolytic therapy. Mosesson’s bench and clinical research activities focused mainly on fibrinogen, fibrin, fibrinolysis, thrombosis, and bleeding. After ending his research activities at the Blood Research Institute of The Blood Center of Wisconsin, he turned to writing Fibrinogen Memoirs to slake his thirst for clarity and exposition.
